This art shows the importance of science, technology, and innovation (STI) in achieving sustainable countryside development. It highlights some of the trailblazing technologies and innovations led by DOST and developed by Filipinos that are responsive to the Sustainable Development Goals (SDGs) on Good Health and Wellbeing (SDG 3), Sustainable Cities and Communities (SDG 11), and Decent Work and Economic Growth (SDG 8). With STI, the quality of life of Filipinos will be improved and the countryside will be developed while maintaining the health of the environment.